Evaluating methods for effective decontamination of central venous access devices needleless connectors in adult hospital patients: A pilot randomised control trial protocol

Ms Julie Flynn1

1Griffith University, Nathan, Australia


The importance of decontaminating needleless connectors prior to accessing central venous access devices is highlighted by clinical practice guidelines. However, the standard  decontamination product/solution  is still lacking. A 70% alcohol wipe is still commonly used for this purpose, however it is unclear if it is an adequate form of NC decontamination. The use of chlorhexidine in alcohol for skin antisepsis has been widely tested and shown to be superior to other antiseptics prior to device insertion; however, research is lacking on the effectiveness of chlorhexidine in alcohol for the decontamination of needleless connectors.

I propose a pilot RCT comparing: a 70% alcohol wipe; a 2% chlorhexidine in 70% alcohol wipe; and a 70% alcohol impregnated cap, to determine which product will best reduce central line associated bloodstream infection.

This study will prepare the procedures and processes for a larger powered randomised control trial.


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The ACIPC is the peak body for Infection Prevention and Control professionals in the Australasian region. Our stated vision is the prevention and control of infection in our communities. We commenced in January 2012 bringing together the various State and Territory infection control associations formerly in AICA (The Australian Infection Control Association) to support and encourage collaboration across Australasia.

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