Gram-negative blood stream infections – challenges and improvement plans in the UK

Ms Patricia Cattini1

1Royal Marsden Nhs Foundation Trust, Cheam, United Kingdom


  1. Introduction

Blood stream infection caused by E.coli and other gram negative infections has been steadily rising in the UK alongside reductions in other infections like MRSA. The UK regulator NHS Improvement has been tasked by the Minister of State for Health to reduce E.coli bacteraemia by 50% by 2021. This poster/presentation will describe the extent of the problem and discuss  initiatives being used in UK communities, hospitals and healthcare settings to bring E.coli bacteraemia numbers under control

  1. Methods

The poster will describe the following areas of work to impact numbers


Urinary catheters

IV Line care

Skin care

Water hygiene


  1. Results

Local and national results to date will be presented along with an overview of the continuing challenges

  1. Discussion

Opinion is divided in the UK as to whether we can really make a difference to the rising numbers of E.coli bacteremia’s.  This is because of the complicated challenges around gram negative sepsis.  Healthcare professionals in the UK are making determined efforts to look at a range of care factors


Pat qualified in 1989 from Charing Cross Hospital. Pat has worked in infection prevention in the UK for 25 years in a variety of settings including acute, specialist and community.

Pat has particular interests in antimicrobial resistance, hand hygiene, decontamination and invasive device care. She holds a Master’s Degree in Infection Prevention from Essex University.

Pat is President of the Infection Prevention Society from Oct 2018. The IPS vision is ‘that no person is harmed by an avoidable infection’.

Pat was awarded the British Journal of Nursing Infection Prevention Nurse of the Year for 2017.

Recent Comments