Inactivation of sexually transmitted pathogens using an automated hydrogen peroxide high level disinfection device for ultrasound probes

Lia Moshkanbaryans 1

Clinical Program Associate, Nanosonics Ltd, Lane Cove West, NSW, Australia


Surface and intracavity ultrasound probe bodies and handles have been shown to be a reservoir for a range of nosocomial pathogens. Recent studies have shown that probes can be contaminated with human papillomavirus (HPV), the causative agent of 99.7% of all cervical cancers and that aldehyde based high-level disinfectants seem to be ineffective against these viruses. A recent study showed that an automated ultrasound probe high level disinfection device (trophon® EPR) completely inactivates HPV making this the only proven high level disinfection system to kill native HPV16 and HPV18 virions. We sought to test the efficacy of the automated device against other clinically relevant sexually transmitted pathogens including Chlamydia trachomatis, HBV, HCV, HIV and Neisseria gonorrhoeae. We demonstrated that the automated device eradicated these microorganisms when tested under normal use, manufacturer recommended conditions. While high-level disinfectants are assumed to inactivate all pathogens except spores, specific testing should be conducted to prove efficacy against clinically relevant organisms, especially those with atypical resistance profiles such as HPV.

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